Anticovidian v.2 COVID-19: Hypothesis of the Lab Origin Versus a Zoonotic Event which can also be of a Lab Origin: https://zenodo.org/record/3988139
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"I want to
put this note here before it is erased, it is very noticeably that theoretical
and complete .....s in that page ridicule the efforts to find the origin of
COVID-19, even being deliberately or really out of their ignorance, unawares
that all the molecular technologies to tweak even a single nucleotide to modify
a single amino acid were already in full existence, while a real practical
experimenter, more aware of the tools than the other three stooges commenting
in the same page, this practical researcher, is then open to investigate the
origins from a Laboratory of such Engineered Pandemic, while the other obtuse
three are not. Here is his comment in full:
"Nikolai
Petrovsky is a Professor in the College of Medicine
and Public Health at Flinders University. He is also Research
Director, Vaxine Pty Ltd
"An
extremely important but still unanswered question is what was
the source of COVID-19 virus. While COVID-19 has close similarities to
SARS and other bat viruses no natural virus matching to COVID-19 has been found
in nature despite an intensive search to find its origins. This raises the very
legitimate question of whether the COVID-19 virus might be the result of human
intervention. Certainly, our and other analyses of the genomic sequence
of the virus do not reveal any artificial gene inserts that would be the
hallmark of a gene jockey, genetic engineers who manipulate or even create
viruses by splicing in artificial inserts into their genome. These are
generally easily recognisable and hence clear
signatures of human intervention in the creation of a virus. The fact that
these artificial inserts are not present has been interpreted by some to mean
this virus is not the result of human manipulation. However, this logic is
incorrect as there are other ways in which humans can manipulate viruses and
that is caused by natural selection. What do I mean? All viruses and bacteria
mutate and adapt to their environment over time, with selection of the fittest
individuals for survival in that particular environment. Take a bat coronavirus that is not infectious to humans, and force its
selection by culturing it with cells that express human ACE2 receptor, such
cells having been created many years ago to culture SARS coronaviruses
and you can force the bat virus to adapt to infect human cells via mutations in
its spike protein, which would have the effect of increasing the strength of
its binding to human ACE2, and inevitably reducing the strength of its binding
to bat ACE2. Viruses in prolonged culture will also develop other random
mutations that do not affect its function. The result of these experiments is a
virus that is highly virulent in humans but is sufficiently different that it
no longer resembles the original bat virus. Because the mutations are acquired
randomly by selection there is no signature of a human gene jockey, but this is
clearly a virus still created by human intervention. My group
in collaboration with other Australian researchers have been using a modelling approach to study the possible evolutionary
origins of COVID-19 by modelling interactions between
its spike protein and a broad variety of ACE2 receptors from many animals and
humans. This work which we will publish on a prepress server next week shows
that the strength of binding of COVID-19 to human ACE2 far exceeds the
predicted strength of its binding to the ACE2 of any of the other species. This points to the virus having been selected for its high
binding to human ACE2. In the absence of evidence of historic human
infections with this virus, which could result in such selection, this either
is a remarkable coincidence or a sign of human intervention. This,
plus the fact that no corresponding virus has been found to exist in nature,
leads to the possibility that COVID-19 is a human-created virus.
It is therefore entirely plausible that the virus was created in the biosecurity facility in Wuhan by selection on cells
expressing human ACE2, a laboratory that was known to be cultivating exotic bat
coronaviruses at the time. Is so the cultured virus
could have escaped the facility either through accidental infection of a staff
member who then visited the fish market several blocks away and there infected
others, or by inappropriate disposal of waste from the facility that either
infected humans outside the facility directly or via a susceptible vector such
as a stray cat that then frequented the market and resulted in transmission
there to humans. Whilst the facts cannot be known at this time, the
nature of this event and its proximity to a high-risk biosecurity
facility at the epicentre of the outbreak demands a
full and independent international enquiry to ascertain whether a virus of this
kind of COVID-19 was being cultured in the facility and might have been
accidentally released."
Last updated: 17
Apr 2020 12:14 pm Declared conflicts of interest: Vaxine Pty Ltd has a COVID-19 vaccine in
advanced preclinical development that is anticipated to commence human clinical
trials in the near future."
Update, the comment by Edward Holmes (a person that seems to be working
hard for the system that released COVID-19, the same as his pals Ian Lipkin, a tool of the system (he is the one assigned
by very corrupt Fauci, NIAID, to discredit Judy Mikovits who demonstrated the contaminated blood supply (and
the vaccines) with fragments of XMRV virus causing ME/CFS), and Garry, another
tool of the system, Andersen and Rambaut, the same,
authors of the opinion and useless scientifically hit-piece called “The
Proximal Origin of Sars-CoV-2”, where all of those corrupt men were already
concluding that COVID-19 was “natural”, when indeed it is NOT “natural” but
ARTIFICIAL), also posted there, basically indicates that Shi Zheng-Li herself is wronging the world because:
"The closest known relative of SARS-CoV-2 is a bat
virus named RaTG13, which was kept at the Wuhan Institute of Virology. There is
some unfounded speculation (my note: By the one that is covering-up that
COVID-19 emerged from her hand and from her lab, Shi Zhengli
herself!!!! Hehee) that this virus was the origin of SARS-CoV-2. However:
(i) RaTG13 was sampled from a different
province of China (Yunnan) to where COVID-19 first appeared; and
(ii) the level of genome sequence
divergence between SARS-CoV-2 and RaTG13 is equivalent to an average of 50
years (and at least 20 years) of evolutionary change.
Hence, SARS-CoV-2 was not derived from RaTG13."
So, this
bring us again to an excellent and thorough research that you can
analyze carefully:
https://nerdhaspower.weebly.com/ratg13-is-fake.html and
its prequel (as well as the very interesting comments by the readers, most of
them also scientists searching the truth, but cloaked in pseudonyms, like the
original writer, for fear of the bullying by the CCP, NIH, NIAID, WHO,
Gates..., which indicates that are top-notch experts filled with fear but at
the same time filled with the desires, as we all are, that the full truth will
emerge, before we all are in this world as if we were living inside China under
the sovereign kingdom of Bill Gates, please DO NOT LET that to happen!!!: https://nerdhaspower.weebly.com/
The only way to reduce
the time needed for a natural and normal strain of virus to achieve with no
previous history such a strong affinity to the human ACE2 and such infectivity
is by a lab intervention, period.
Tracking history and
their participants for the moment of truth to held the
culprits accountable, and certainly their accomplices too, such as those three
useless individuals mentioned at the start."
"I humbly ask you
to be well informed by watching these videos, to know from where the stumping
over the whole humanity is coming: Trump, Gates, and all of them, cut with the
same scissors, all of them want to "vaccinate" the whole of humanity:
to https://www.youtube.com/watch?v=o7A_cMpKm6w, and
here is the whole set of information to be well informed: https://www.corbettreport.com/gates; Gates
and all of them are planning the destiny of humanity, shame on them
all!!!: https://www.youtube.com/watch?v=3VAj3hsdTtw (Gates
says at minute 7:00 that his "philanthropy" for him is paying him
back: 20:1 in revenues!!!, so, for his own words will he be indicted, even if
later he pays lots to cover for his absurd statements and "fact
changing" whatever stupidity it is that he said or did, the very clear
evidence of this is that he denied knowing Epstein, even if there are lots of
"tracks" of his close acquaintance with him, that is just one
evidence that Gates lies about his real intentions all the way through his
elbows!!!, but say NO to any attempt of making a vaccination mandatory to you
and to your little ones, for the benefit, at least, of the manhood of our
generation, which as everything else, is just going down the drain...)."
"How important is
the unique poly basic insert and where does it come
from? https://archive.vn/Yl3Cw
"It is just
strange that all the related Bat, Civet cat, Raccoon and Pangolin sequences
lack the insert of 12 nucleotides creating the extra basic sequence PRRA making
it more sensitive for various human proteases and mind you this is not a
mutation but insertion of 12 nucleotides (presumably increasing the virulence):
see https://doi.org/10.1016/j.molcel.2020.04.022
Where does this insert comes from? Probably not
a Bat coronavirus and a Camel coronavirus
(MERS) meeting each other in a Pangolin on the market in Wuhan giving a cross
over SARS-Cov-2. On the other hand-but certainly no evidence this
happened- this insert can be rationalized and made by a molecular biologist
starting for instance with a Bat sequence and some cut and paste. Better
suggestions are welcome….
The insertion of a Furin (also plasmin, trypsin, Xa) protease cleavage
site in the spike glycoprotein (aa682 – aa689) is strikingly novel in
SARS-CoV-2, has not been found in other related coronaviruses
(so perhaps handmade by virologists, who were playing with this insert as they
did earlier on other viruses) and is supposed to make the virus highly
virulent. So is it a selection criterion that an antibody also protects this
unique (hand made?!) Furin cleavage site?
The unique insert in
SARS-Cov2 is not a mutation and is not present in most closely related corona
viruses. However, similar polybasic cleavage sites (for furin
and other human proteases) are well known in numerous other viruses and its
cleavage is essential for infection: https://doi.org/10.1002/cti2.1073
It has been suggested
that most likely the insert in SARS-Cov2 has been acquired by recombination,
but it has not been indicated how and from which virus/species: https://doi.org/10.1101/2020.03.02.974139
Virologists publish
for more than a decade that they engineer polybasic cleavage sites in viral
genomes to enhance pathogenicity: e.g. in 2011, using
recombinant technology in a lab an avirulent avian
influenza virus could be converted into a highly pathogenic phenotype (with
engineered polybasic cleavage site): https://doi.org/10.1099/vir.0.031591-0 "
The Devilish Event
201: https://www.youtube.com/watch?v=LBuP40H4Tko, participant
from minute 30:50... S.O.B.
https://web.archive.org/web/20200512220911/https://plandemicmovie.com/ (Before the NIAID, WHO, Gates hacked it, as per the 18th of May,
2020).
Notice: It is
noticeably that also, currently, when I do a search with an a posteriori found,
supposedly related sequence to the one under our consideration, I obtain again,
mostly references from BACTERIA, as in my initial claim: https://www.google.com/search?q=furin+sequence+R-AAR-&oq=furin+sequence+R-AAR-&"
Previously available
at:
*****
Kind regards,
Karl
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