Anticovidian v.2 COVID-19: Hypothesis of the Lab Origin Versus a Zoonotic Event which can also be of a Lab Origin: https://zenodo.org/record/3988139
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*****Removed content (with my update of the names of the other inane tools of the system):
"I want to put this note here before it is erased, it is very noticeably that theoretical and complete .....s in that page ridicule the efforts to find the origin of COVID-19, even being deliberately or really out of their ignorance, unawares that all the molecular technologies to tweak even a single nucleotide to modify a single amino acid were already in full existence, while a real practical experimenter, more aware of the tools than the other three stooges commenting in the same page, this practical researcher, is then open to investigate the origins from a Laboratory of such Engineered Pandemic, while the other obtuse three are not. Here is his comment in full:
"Nikolai Petrovsky is a Professor in the College of Medicine and Public Health at Flinders University. He is also Research Director, Vaxine Pty Ltd
"An extremely important but still unanswered question is what was the source of COVID-19 virus. While COVID-19 has close similarities to SARS and other bat viruses no natural virus matching to COVID-19 has been found in nature despite an intensive search to find its origins. This raises the very legitimate question of whether the COVID-19 virus might be the result of human intervention. Certainly, our and other analyses of the genomic sequence of the virus do not reveal any artificial gene inserts that would be the hallmark of a gene jockey, genetic engineers who manipulate or even create viruses by splicing in artificial inserts into their genome. These are generally easily recognisable and hence clear signatures of human intervention in the creation of a virus. The fact that these artificial inserts are not present has been interpreted by some to mean this virus is not the result of human manipulation. However, this logic is incorrect as there are other ways in which humans can manipulate viruses and that is caused by natural selection. What do I mean? All viruses and bacteria mutate and adapt to their environment over time, with selection of the fittest individuals for survival in that particular environment. Take a bat coronavirus that is not infectious to humans, and force its selection by culturing it with cells that express human ACE2 receptor, such cells having been created many years ago to culture SARS coronaviruses and you can force the bat virus to adapt to infect human cells via mutations in its spike protein, which would have the effect of increasing the strength of its binding to human ACE2, and inevitably reducing the strength of its binding to bat ACE2. Viruses in prolonged culture will also develop other random mutations that do not affect its function. The result of these experiments is a virus that is highly virulent in humans but is sufficiently different that it no longer resembles the original bat virus. Because the mutations are acquired randomly by selection there is no signature of a human gene jockey, but this is clearly a virus still created by human intervention. My group in collaboration with other Australian researchers have been using a modelling approach to study the possible evolutionary origins of COVID-19 by modelling interactions between its spike protein and a broad variety of ACE2 receptors from many animals and humans. This work which we will publish on a prepress server next week shows that the strength of binding of COVID-19 to human ACE2 far exceeds the predicted strength of its binding to the ACE2 of any of the other species. This points to the virus having been selected for its high binding to human ACE2. In the absence of evidence of historic human infections with this virus, which could result in such selection, this either is a remarkable coincidence or a sign of human intervention. This, plus the fact that no corresponding virus has been found to exist in nature, leads to the possibility that COVID-19 is a human-created virus. It is therefore entirely plausible that the virus was created in the biosecurity facility in Wuhan by selection on cells expressing human ACE2, a laboratory that was known to be cultivating exotic bat coronaviruses at the time. Is so the cultured virus could have escaped the facility either through accidental infection of a staff member who then visited the fish market several blocks away and there infected others, or by inappropriate disposal of waste from the facility that either infected humans outside the facility directly or via a susceptible vector such as a stray cat that then frequented the market and resulted in transmission there to humans. Whilst the facts cannot be known at this time, the nature of this event and its proximity to a high-risk biosecurity facility at the epicentre of the outbreak demands a full and independent international enquiry to ascertain whether a virus of this kind of COVID-19 was being cultured in the facility and might have been accidentally released."
Last updated: 17 Apr 2020 12:14 pm Declared conflicts of interest: Vaxine Pty Ltd has a COVID-19 vaccine in advanced preclinical development that is anticipated to commence human clinical trials in the near future."
Update, the comment by Edward Holmes (a person that seems to be working hard for the system that released COVID-19, the same as his pals Ian Lipkin, a tool of the system (he is the one assigned by very corrupt Fauci, NIAID, to discredit Judy Mikovits who demonstrated the contaminated blood supply (and the vaccines) with fragments of XMRV virus causing ME/CFS), and Garry, another tool of the system, Andersen and Rambaut, the same, authors of the opinion and useless scientifically hit-piece called “The Proximal Origin of Sars-CoV-2”, where all of those corrupt men were already concluding that COVID-19 was “natural”, when indeed it is NOT “natural” but ARTIFICIAL), also posted there, basically indicates that Shi Zheng-Li herself is wronging the world because:
"The closest known relative of SARS-CoV-2 is a bat virus named RaTG13, which was kept at the Wuhan Institute of Virology. There is some unfounded speculation (my note: By the one that is covering-up that COVID-19 emerged from her hand and from her lab, Shi Zhengli herself!!!! Hehee) that this virus was the origin of SARS-CoV-2. However:
(i) RaTG13 was sampled from a different province of China (Yunnan) to where COVID-19 first appeared; and
(ii) the level of genome sequence divergence between SARS-CoV-2 and RaTG13 is equivalent to an average of 50 years (and at least 20 years) of evolutionary change.
Hence, SARS-CoV-2 was not derived from RaTG13."
So, this bring us again to an excellent and thorough research that you can analyze carefully:
https://nerdhaspower.weebly.com/ratg13-is-fake.html and its prequel (as well as the very interesting comments by the readers, most of them also scientists searching the truth, but cloaked in pseudonyms, like the original writer, for fear of the bullying by the CCP, NIH, NIAID, WHO, Gates..., which indicates that are top-notch experts filled with fear but at the same time filled with the desires, as we all are, that the full truth will emerge, before we all are in this world as if we were living inside China under the sovereign kingdom of Bill Gates, please DO NOT LET that to happen!!!: https://nerdhaspower.weebly.com/
The only way to reduce the time needed for a natural and normal strain of virus to achieve with no previous history such a strong affinity to the human ACE2 and such infectivity is by a lab intervention, period.
Tracking history and their participants for the moment of truth to held the culprits accountable, and certainly their accomplices too, such as those three useless individuals mentioned at the start."
"I humbly ask you to be well informed by watching these videos, to know from where the stumping over the whole humanity is coming: Trump, Gates, and all of them, cut with the same scissors, all of them want to "vaccinate" the whole of humanity: to https://www.youtube.com/watch?v=o7A_cMpKm6w, and here is the whole set of information to be well informed: https://www.corbettreport.com/gates; Gates and all of them are planning the destiny of humanity, shame on them all!!!: https://www.youtube.com/watch?v=3VAj3hsdTtw (Gates says at minute 7:00 that his "philanthropy" for him is paying him back: 20:1 in revenues!!!, so, for his own words will he be indicted, even if later he pays lots to cover for his absurd statements and "fact changing" whatever stupidity it is that he said or did, the very clear evidence of this is that he denied knowing Epstein, even if there are lots of "tracks" of his close acquaintance with him, that is just one evidence that Gates lies about his real intentions all the way through his elbows!!!, but say NO to any attempt of making a vaccination mandatory to you and to your little ones, for the benefit, at least, of the manhood of our generation, which as everything else, is just going down the drain...)."
"How important is the unique poly basic insert and where does it come from? https://archive.vn/Yl3Cw
"It is just strange that all the related Bat, Civet cat, Raccoon and Pangolin sequences lack the insert of 12 nucleotides creating the extra basic sequence PRRA making it more sensitive for various human proteases and mind you this is not a mutation but insertion of 12 nucleotides (presumably increasing the virulence): see https://doi.org/10.1016/j.molcel.2020.04.022
Where does this insert comes from? Probably not a Bat coronavirus and a Camel coronavirus (MERS) meeting each other in a Pangolin on the market in Wuhan giving a cross over SARS-Cov-2. On the other hand-but certainly no evidence this happened- this insert can be rationalized and made by a molecular biologist starting for instance with a Bat sequence and some cut and paste. Better suggestions are welcome….
The insertion of a Furin (also plasmin, trypsin, Xa) protease cleavage site in the spike glycoprotein (aa682 – aa689) is strikingly novel in SARS-CoV-2, has not been found in other related coronaviruses (so perhaps handmade by virologists, who were playing with this insert as they did earlier on other viruses) and is supposed to make the virus highly virulent. So is it a selection criterion that an antibody also protects this unique (hand made?!) Furin cleavage site?
The unique insert in SARS-Cov2 is not a mutation and is not present in most closely related corona viruses. However, similar polybasic cleavage sites (for furin and other human proteases) are well known in numerous other viruses and its cleavage is essential for infection: https://doi.org/10.1002/cti2.1073
It has been suggested that most likely the insert in SARS-Cov2 has been acquired by recombination, but it has not been indicated how and from which virus/species: https://doi.org/10.1101/2020.03.02.974139
Virologists publish for more than a decade that they engineer polybasic cleavage sites in viral genomes to enhance pathogenicity: e.g. in 2011, using recombinant technology in a lab an avirulent avian influenza virus could be converted into a highly pathogenic phenotype (with engineered polybasic cleavage site): https://doi.org/10.1099/vir.0.031591-0 "
The Devilish Event 201: https://www.youtube.com/watch?v=LBuP40H4Tko, participant from minute 30:50... S.O.B.
https://web.archive.org/web/20200512220911/https://plandemicmovie.com/ (Before the NIAID, WHO, Gates hacked it, as per the 18th of May, 2020).
Notice: It is noticeably that also, currently, when I do a search with an a posteriori found, supposedly related sequence to the one under our consideration, I obtain again, mostly references from BACTERIA, as in my initial claim: https://www.google.com/search?q=furin+sequence+R-AAR-&oq=furin+sequence+R-AAR-&"
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